What Have We Learned from Risk-Reducing Salpingo-oophorectomy?
نویسندگان
چکیده
منابع مشابه
What have we learned from risk-reducing salpingo-oophorectomy?
In this issue of the Journal, Rebbeck et al. (1) have provided us with a meticulously executed, up-to-date meta-analysis that quantifies the reductions in the risks of breast and ovarian/fallopian tube cancer that follow risk-reducing salpingo-oophorectomy (RRSO) in BRCA1 and BRCA2 (BRCA1/2) mutation carriers. Their conclusion — " The summary risk reduction estimates presented here indicate tha...
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متن کاملBone density loss after risk reducing salpingo-oophorectomy
Women undergoing risk-reducing salpingo-oophorectomy through the Prince of Wales Hospital Hereditary Cancer Clinic are offered enrolment in a prospective study of bone mineral density (BMD), markers of bone metabolism and cardio-vascular risk factors. Participants are invited to enroll a friend who has ovaries in situ and are aged within five years of the participant as a control population. Lu...
متن کاملRisk-reducing salpingo-oophorectomy for BRCA mutation carriers.
It has been twenty years since the region of the BRCA1mutationwas identified on chromosome 17q. There are now over 3000 risk reducing salpingo-oophorectomy (RRSO) cases reported and an estimated 150 cases describing unsuspected cancers of the ovaries and tubes or in situ lesions. Connor et al. in their current study add to the literature on RRSO outcomes [1]. They report on 345 cases of RRSO in...
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ژورنال
عنوان ژورنال: JNCI Journal of the National Cancer Institute
سال: 2009
ISSN: 0027-8874,1460-2105
DOI: 10.1093/jnci/djn476